Detall de la convocatòria

Expressió d'interès - Expression of interest

Característiques

Característica
Objectiu de la convocatòria
The CRI Clinical Innovator program aims Aims to advance both new therapy testing and deeper understanding of the immune system’s role in cancer by supporting pioneering immunotherapy clinical trials designed and led by academic researchers. Its goal is to improve patient outcomes, address areas with high unmet medical needs, and generate critical mechanistic insights that guide the future of cancer treatment.
Característiques principals
  • Funds innovative Phase I/II or Phase II clinical studies with a strong emphasis on novel immunotherapy approaches, mechanistic investigations into clinical response and the discovery and/or validation of predictive biomarkers.
  • Provides strategic guidance on trial design to maximize translational impact and rigor. CRI encourages data sharing through platforms such as the CRI iATLAS.
  • Supports studies that integrate standardized sample collection, correlative assays, and advanced data analyses to ensure reproducible and impactful findings.

    PROGRAM NOTE
    In partnership with the Chordoma Foundation, CRI also welcomes proposals focused on accelerating the development of effective treatments and ultimately a cure for chordoma. CF has chordoma models and banked tumor samples that are available to the research community. Successful applications in this area will be co-funded by CRI and CF.
    • Lloc de presentació
    HMRIB and PSMAR staff who need more information should contact:
    Research Grants and Contracts Office. C/ Doctor Aiguader, 88. 08003 Barcelona. Tel.: 93.316.04.00.
    Carol Barnwell: [email protected] Ext.: 1670
    Marta López: [email protected] Ext.: 1576
    Convocatòria (URL)
    https://www.cancerresearch.org/clinical-innovator
    Application Portal: https://cri.us-1.smartsimple.com/s_Login.jsp
    Requisits
    Candidates must be the Principal Investigator (PI) of the proposed study.
    CRI has no citizenship restrictions, and research supported by the award may be conducted at medical schools or research centers in the United States or abroad. Please note that CRI does not support research at for-profit institutions.
    Dotació
    Up to $1M per trial. Funding may be used for investigator salary, patient costs, supplies, correlative assays, and data analyses. Payments are structured in milestones to ensure steady progress and trial completion.
    Documentació
    An initial Protocol Concept must be submitted electronically. It must include the following documents as separate PDF files:
  • A brief protocol concept (maximum 2 pages, excluding study schema and references) including study rationale, primary objectives and secondary objectives, number of patients to be treated, patient eligibility criteria, sample collection and biostatistics plan.
  • A separate 1-page study schema should be uploaded outlining the clinical design.
  • A brief translational plan (maximum 1 page, excluding references) with its aims and rationale, assays intended to use and samples to be tested.
  • Biographical sketches for PI(s) and co-PI(s) (limit bibliography to past 5 years or publications relevant to proposed study).
    Formatting Guidelines: Any documents you attach to your online application form must be typed single-space using a 12 point or larger font size.
    • AVÍS IMPORTANT
    Applications must be submitted by 11:59 p.m. Eastern Time on the deadline date. If the deadline falls on a weekend, applications will be accepted until the end of the following Monday. It is strongly recommended to submit as early as possible to allow ample time for completion.

    Arxius

    Arxiu
    CRI-Invention-Disclosure-Form-1-2025.pdf
    Annual-Invention-Update-Form-1-2025.pdf
    Revenue-Sharing-Agreement.pdf